Hu Recom NGF-beta, 100 µg

A laboratory reagent from STEMCELL Technologies, Human Recombinant NGF-beta is supplied as a solid. The protein plays a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and supporting neuron migration.

Biological activity was assessed by its ability to promote proliferation of TF-1 cells grown in GM-CSF free medium. Proliferation was measured after 67 hours of culture using a fluorometric assay method, with the EC50 — the effective concentration at which cell proliferation reaches 50% of maximum — reported as 0.54 ng/mL. The protein is a homodimer of 13.6 kDa subunits with a predicted total molecular mass of 27.3 kDa, demonstrated by SDS-PAGE under reducing and non-reducing conditions visualized with Coomassie Blue staining.

Per the manufacturer's Safety Data Sheet, the chemical is not considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) and is not classified as a hazardous substance or mixture according to the Globally Harmonized System. It is stable under recommended transport and storage conditions, which are described on the Product Information Sheet. The product is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, ADR, or ADN.