Hu Recom Myostatin, 10 µg

STEMCELL Technologies provides Human Recombinant Myostatin, a member of the TGF-β superfamily. The manufacturer describes it as affecting the lipid catabolic metabolism of adipocytes and inhibiting preadipocyte differentiation. Biological activity was assessed by the ability of the protein to inhibit proliferation of MPC-11 cells, with cell viability measured after 66 hours using a fluorometric assay method; the reported EC50 in this example is 12 ng/mL, defined as the effective concentration at which cell viability reaches 50% of maximum. Purity was evaluated by resolving 1 μg of the protein with SDS-PAGE under reducing and non-reducing conditions, visualized by Coomassie Blue staining. The product is listed for use in research areas including the differentiation of human MSCs into adipocytes, where it appears as a loading component within the supported workflow.