Hu Recom IL-9, 50 µg

Human Recombinant IL-9 (Interleukin-9) is a pleiotropic cytokine produced primarily by Th9 and Th2 CD4+ T cells, with contributions from mast cells and innate lymphoid cells. This 50 µg preparation from STEMCELL Technologies supports immunology research focused on allergic inflammation, mast cell biology, parasite clearance, and the tumor microenvironment, where IL-9 has been linked to Hodgkin lymphoma and certain solid tumor models.

The protein is supplied as a lyophilized powder for flexible reconstitution. Working stocks are typically prepared in sterile PBS with 0.1% BSA as a carrier protein, and the reconstituted material is stored at -20°C to -80°C to preserve bioactivity across multiple freeze-thaw cycles. Researchers confirm functional activity in cell culture using IL-9-dependent proliferation assays or STAT phosphorylation readouts in target cell lines.

For experimental use, IL-9 is commonly paired with IL-2, IL-4, and TGF-β in Th9 polarization protocols, or applied to mast cell and ILC2 cultures to study downstream signaling through the IL-9 receptor (IL-9R) and JAK-STAT pathway. Each lot is quality controlled for purity and endotoxin level, supporting reproducible stimulation of primary human lymphocytes and engineered reporter systems in research use only applications.