Hu Recom IL-21, 100 µg

STEMCELL Technologies offers Human Recombinant IL-21, a recombinant cytokine described as regulating immunoglobulin production and the differentiation of the pro-inflammatory Th17 cell population. According to the manufacturer's product information, the biological activity of Human Recombinant IL-21 was tested by its ability to inhibit the proliferation of Mino cells, with cell proliferation measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum, and the EC50 in the example shown is less than 0.5 ng/mL.

In SDS-PAGE analysis, 2 μg of Human Recombinant IL-21 was resolved under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. The protein has a predicted molecular mass of 15.4 kDa. Supporting workflows referenced in the source material include immunodensity negative selection cocktails, as well as the immunomagnetic negative isolation of untouched human T cells and untouched human CD8+ T cells.