Hu Recom IL-1 beta, ACF, 10 µg

STEMCELL Technologies supplies this Human Recombinant IL-1 beta (Interleukin-1 beta) protein in an Animal Component-Free (ACF) formulation, providing researchers with a defined, xeno-free reagent for sensitive cell culture workflows. IL-1 beta is a potent pro-inflammatory cytokine that drives fever, leukocyte recruitment, and acute-phase signaling, and is widely used to activate immune cell populations, model inflammatory disease in vitro, and support differentiation studies in hematopoietic and mesenchymal systems.

The recombinant protein is supplied as a 10 ug vial, enabling reproducible dose-response experiments and consistent stimulation of monocytes, macrophages, dendritic cells, and T lymphocytes. Because the ACF manufacturing process avoids animal-derived raw materials, this cytokine is appropriate for translational pipelines where traceability and regulatory documentation are priorities, including stem cell-derived disease models and clinical-grade process development. Researchers use it for flow cytometry-based immune phenotyping, signaling studies of the NLRP3 inflammasome and NF-kB pathway, and co-culture experiments pairing activated immune cells with organoids or tumor spheroids.

The format supports long-term storage at -20 degrees C or colder, and single-use aliquots are recommended once reconstituted to preserve biological activity through repeated freeze-thaw cycles.