Hu Recom DKK-1, 1000 µg

STEMCELL Technologies supplies this Human Recombinant DKK-1, His-tag as a laboratory reagent for research applications. The manufacturer's safety data sheet classifies the product as not a hazardous substance or mixture according to the Globally Harmonized System (GHS). The material is provided as a solid powder.

DKK-1 is described by the manufacturer as a regulator of embryonic development that supports the generation of myeloid-derived suppressor cells, and is presented as a WNT pathway inhibitor. Biological activity was tested by the ability of the protein to inhibit Wnt3a-induced alkaline phosphatase production by C3H10T1/2 cells, measured using a fluorometric assay method. The EC50, defined as the effective concentration of the growth factor at which alkaline phosphatase production is at 50% of maximum, is less than 4 μg/mL in the example shown.

Products are for research use only and are not intended for human or animal diagnostic or therapeutic uses unless otherwise stated. STEMCELL Technologies Canada's quality management system is certified to ISO 13485. Storage guidance is to keep containers tightly closed in a dry, cool and well-ventilated place; the product is stable under normal conditions.