Hu Recom BMP-2, 100 µg

STEMCELL Technologies Human Recombinant BMP-2 is a recombinant human bone morphogenetic protein supplied for stem cell research applications. According to the manufacturer, BMP-2 directs human pluripotent stem cells towards various cell types, including extra-embryonic endoderm, mesenchymal cells, and chondrocytes.

The biological activity of Human Recombinant BMP-2 was tested by its ability to promote alkaline phosphatase production in ATDC-5 cells, as measured using a fluorometric assay method. The EC50 is defined by the manufacturer as the effective concentration of the growth factor at which alkaline phosphatase production is at 50% of maximum, and in the reported example the EC50 is 0.09 μg/mL. The manufacturer states that Human Recombinant BMP-2 has a predicted molecular mass of 26 kDa.

This product is designed for use in research areas related to stem cell differentiation workflows, and is listed by the manufacturer alongside complementary growth factors including Activin A, basic fibroblast growth factor, and vascular endothelial growth factor. Supporting information and directions for use are available in the Product Information Sheet.