Hu Recom bFGF, 10 µg

From STEMCELL Technologies, this Human Recombinant bFGF is supplied as a solid powder intended for use as a laboratory reagent. The manufacturer states that the product is for research use only and is not intended for human or animal diagnostic or therapeutic uses unless otherwise stated, and notes that its quality management system is certified to ISO 13485.

The protein supports the maintenance of undifferentiated human embryonic stem cells and stimulates these cells to form neural rosettes, according to the manufacturer. Biological activity is tested by the protein's ability to promote proliferation of BALB/c 3T3 cells, measured using a fluorometric assay method, with the EC50 defined as the effective concentration at which proliferation reaches 50% of maximum. The manufacturer's example reports an EC50 of 0.1 ng/mL. The protein has a predicted molecular mass of 17.1 kDa, as visualised by SDS-PAGE under reducing and non-reducing conditions with Coomassie Blue staining.

The product is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS) and is stable under normal conditions. Third-party distributors categorise this product within the stem cell identification and isolation area.