Hu Recom Betacellulin, 1000 µg

STEMCELL Technologies supplies Human Recombinant Betacellulin, a member of the EGF family of growth factors. The recombinant protein induces neural stem cell proliferation and prevents spontaneous differentiation in culture.

Biological activity was tested by its ability to promote the proliferation of BALB/c 3T3 cells, with cell proliferation measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum; in the tested example the EC50 is less than 0.01 ng/mL. The protein has also been resolved with SDS-PAGE under reducing and non-reducing conditions and visualized by Coomassie Blue staining.

This product supports several research workflows, including serum-free medium for the differentiation of human ES and iPS cells to pancreatic progenitor cells, culture of human mammospheres and tumorspheres, and culture of human mammary epithelial cells.