Hu/Ms Recom TGF-beta 3, 4x250 µg

STEMCELL Technologies supplies this Human/Mouse Recombinant TGF-beta 3 as a laboratory reagent, manufactured by STEMCELL Technologies Canada Inc. in Vancouver, British Columbia, Canada. According to the safety data sheet, the product is provided as a liquid and is not considered hazardous under the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200), nor is it classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS).

Composition information lists Ethyl Alcohol (CAS 64-17-5) at 20% by weight, with the exact percentage withheld as a trade secret. Workplace exposure limits for this component include an ACGIH TLV STEL of 1000 ppm, an OSHA PEL TWA of 1000 ppm (TWA 1900 mg/m³), and a NIOSH IDLH of 3300 ppm. The mixture is reported as chemically stable under recommended transport or storage conditions and should be stored according to the Product Information Sheet (PIS).

Toxicological data give an ATEmix (oral) of 35,300.00 mg/kg, and 100% of the mixture consists of ingredient(s) of unknown toxicity. For Ethyl Alcohol, an oral LD50 of 7060 mg/kg (Rat) and inhalation LC50 values of 116.9 mg/L (Rat, 4 h) and 133.8 mg/L (Rat, 4 h) are listed, with target organ effects including the liver, respiratory system, eyes, skin, central nervous system, blood, and reproductive system. Aquatic toxicity data include fish LC50 values of 12.0 - 16.0 mL/L (96 h, Oncorhynchus mykiss), >100 mg/L (96 h, Pimephales promelas), and 13400 - 15100 mg/L (96 h, Pimephales promelas), together with a crustacean LC50 of 9268 - 14221 mg/L (48 h, Daphnia magna) and an EC50 of 2 mg/L (48 h, Daphnia magna). Ethyl Alcohol is listed as A3 by ACGIH, Group 1 by IARC, Known by NTP, and X by OSHA for carcinogenicity.