Hu/Ms Recom FGF-8B, ACF, 25 µg

STEMCELL Technologies supplies a human/mouse recombinant FGF-8B preparation for laboratory research use. FGF-8B regulates gastrulation, epithelial-mesenchymal transition, and mesenchymal to epithelial differentiation during embryonic development.

Biological activity was tested by its ability to promote the proliferation of NR6R 3T3 cells in the presence of heparin, with cell proliferation measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum; in the example provided, the EC50 is 0.915 ng/mL. SDS-PAGE analysis under reducing and non-reducing conditions, visualized by Coomassie Blue staining, shows a predicted molecular mass of 22.5 kDa.

The product is supplied as a solid and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). It is stable under normal conditions and is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, ADR, or ADN.