Hu/Ms Recom FGF-8B, ACF, 1000 µg

Manufactured by STEMCELL Technologies Canada Inc., Human/Mouse Recombinant FGF-8B, ACF is supplied as a laboratory reagent intended for research use. The product is presented as a solid and is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). It is described as stable under normal conditions, and storage should be carried out in accordance with the information listed on the Product Information Sheet (PIS).

FGF-8B is described in research as a regulator of gastrulation, epithelial–mesenchymal transition, and mesenchymal to epithelial differentiation during embryonic development. The biological activity of this Human/Mouse Recombinant FGF-8B, ACF preparation was tested by its ability to promote the proliferation of NR6R 3T3 cells in the presence of heparin, with cell proliferation quantified using a fluorometric assay method. The EC50 — defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum — was determined to be 0.915 ng/mL in the reported example.

The protein has a predicted molecular mass of 22.5 kDa, and an analytical load of 1 μg was resolved by SDS-PAGE under reducing (+) and non-reducing (−) conditions and visualized with Coomassie Blue staining. Specific test data for inhalation, eye contact, skin contact, and ingestion routes are listed as not available, and the product is not regulated for transport by DOT, TDG, MEX, ICAO, IATA, IMDG, RID, ADR, or ADN.