Eltrombopag, 1 mg

Offered by STEMCELL Technologies, this laboratory chemical acts as a thrombopoietin receptor (TpoR) agonist and an iron chelator. The compound carries the synonym SB497115 and is identified by CAS No. 496775-61-2, with a molecular formula of C25H22N4O4 and a molecular weight of 442.5. It presents as a crystalline solid and is recommended for use as a laboratory chemical.

According to the manufacturer's Safety Data Sheet, the substance is classified as acutely toxic if swallowed (Category 4), causes serious eye damage (Category 1), and may cause damage to organs through prolonged or repeated exposure. The calculated ATEmix (oral) value is 500.00 mg/kg, and the compound is described as very toxic to aquatic life with long lasting effects. Recommended precautions include avoiding contact with skin and eyes, wearing eye protection, washing hands thoroughly after handling, and not eating, drinking, or smoking during use. In case of eye contact, rinse cautiously with water for several minutes and immediately call a Poison Center or doctor; if swallowed, call a Poison Center or doctor if feeling unwell and rinse the mouth.

Solubility information indicates the compound is soluble in DMF at 1 mg/mL, in DMF:PBS (pH 7.2) at a 1:3 ratio at 0.25 mg/mL, in DMSO at 20 mg/mL, and in ethanol at 0.1 mg/mL. The product is stable under recommended transport or storage conditions, which should be in accordance with the Product Information Sheet.