Dibutyryl-cAMP, 500 mg

STEMCELL Technologies supplies this cell-permeable cyclic AMP (cAMP) analog, which activates cAMP-dependent protein kinases. Provided as the sodium salt, the compound has a chemical formula of C₁₈H₂₃N₅O₈P · Na, a molecular weight of 491.4 g/mol, and a purity of ≥ 95%. It is supplied as a crystalline solid and is stable for 12 months from the date of receipt when stored at -20°C and protected from prolonged exposure to light; for long-term storage, use of a desiccant is recommended. Alternative names for the molecule include Bucladesine and DC 2797, with CAS Number 16980-89-5.

Published research applications focus on differentiation. The compound induces morphological differentiation of astrocytes and intrinsic axon growth in both peripheral and central nervous systems, and it stimulates neurite outgrowth in PC12 cells. In a model of experimental autoimmune encephalomyelitis, it suppresses disease development by reducing demyelination and mobilizing neural stem cells in the subventricular zone toward demyelinated plaques. The product is intended for research use only.