Custom LNA Oligo manual design (0.250) - 5' 2'-Fluoro C

This custom LNA-enhanced oligonucleotide from QIAGEN is configured for manual design with a 5' 2'-Fluoro C modification, sitting within the brand's Assay Technologies consumables range. Manual design configurations allow researchers to specify their own sequence rather than selecting from a fixed catalogue of predesigned options.

According to QIAGEN, the high affinity of an LNA-enhanced oligonucleotide for its complementary sequence produces dramatically improved specificity and sensitivity compared with traditional DNA or RNA oligos. The manufacturer states that, in many cases, LNA-enhanced oligos can be used to distinguish between sequences differing by only a single nucleotide, a capability that can be critical for studies involving short or very similar sequences. Ordering for the manual design variant is handled directly through QIAGEN rather than via standard catalogue purchase, with further information available from the company's support team.