CoV-2 Rec N Protein (HEK) 100ug

Produced by STEMCELL Technologies, this recombinant protein is expressed in HEK293 cells and corresponds to the full-length nucleocapsid protein (amino acids Met1-Ala419) of the novel human coronavirus SARS-CoV-2/2019-nCoV. It is one of four structural proteins encoded by the SARS-CoV-2 genome, transcribed from the viral "N" gene, and is the protein that interacts with RNA to form the nucleocapsid. The protein forms a homo-oligomer, and both the monomer and the oligomer can interact with RNA. It also interacts with the membrane (M) protein after host cell infection, during packaging of the positive-strand viral genome RNA into the ribonucleocapsid during virion assembly.

Alternative names include Nucleocapsid protein, NC, Protein N, and N Protein. The UniProt accession number is P0DTC9. The protein has a predicted molecular mass of 47.0 kDa, with an observed band size of ~50 kDa by SDS-PAGE under reducing conditions visualized by Coomassie Blue staining. Purity by SDS-PAGE is ≥ 90%. The product is supplied lyophilized from a 0.2 μm-filtered solution containing Tris-HCl, NaCl, and trehalose at pH 7.4. Activity data are not available. To prepare, centrifuge the vial before opening and reconstitute in sterile water to 0.1–1.0 mg/mL without vortexing; store the reconstituted product at 2–8°C for up to one week. Unopened product should be stored at -20°C to -80°C and is stable until the expiry date on the label.

For research use only.