Anti-ZP2 Antibody

ZP2 (Zona Pellucida Glycoprotein 2) is a key structural component of the zona pellucida, the glycoprotein coat surrounding mammalian oocytes that mediates critical steps in fertilization. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against ZP2 and validated for Western blot detection across human, mouse, and rat samples.

Supplied as 100 µl of a 1 mg/ml stock in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, the reagent is ready to dilute directly into standard WB workflows. Polyclonal reactivity broadens recognition of multiple epitopes on the ZP2 glycoprotein, useful when examining oocyte lysates, ovarian tissue, or zona pellucida preparations.

ZP2 serves as the primary sperm receptor before fertilization and is cleaved by ovastacin after gamete fusion to block polyspermy, so the antibody is relevant to reproductive biology, fertility research, contraceptive development, and mechanistic studies of fertilization failure. Store refrigerated; protect from light and avoid repeated freeze-thaw cycles.