Anti-CR1 Antibody [KT23]

The Anti-CR1 Antibody [KT23] from Antibodies.com is a mouse monoclonal IgG1 reagent raised against human Complement Receptor Type 1 (CD35), supplied as 100 µg in liquid format for flow cytometry. The KT23 clone binds an extracellular epitope on CD35 and labels erythrocytes, B lymphocytes, monocytes, neutrophils, and selected T cell subsets, supporting studies of complement-mediated immune complex clearance, autoimmune conditions such as systemic lupus erythematosus, and erythrocyte rosetting in malaria research.

For FACS workflows, aliquot the unconjugated reagent and refrigerate for short-term use or freeze at -20 °C in single-use vials to preserve activity across freeze-thaw cycles. Investigators typically titrate KT23 between 0.5 and 5 µg per 10⁶ cells, making it applicable to immunophenotyping peripheral blood mononuclear cells and characterizing CR1 expression on leukocyte populations in vitro.