Anti-ZNRF2 Antibody

Raised in rabbit against the C-terminal region of ZNRF2, this unconjugated polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.3, packaged as 100 µl per vial.

ZNRF2 (Zinc And Ring Finger 2) is a transmembrane E3 ubiquitin ligase expressed in neurons of the central nervous system, where it has been implicated in AMPA receptor trafficking, synaptic plasticity, and the regulation of amyloid precursor protein processing relevant to neurodegenerative disease research.

The antibody has been validated for Western blot detection of the target in human, mouse, and rat samples, supporting comparative studies of ligase expression across species.

For best results, store the vial at -20 °C in single-use aliquots to limit freeze-thaw cycles of the stock solution, and avoid prolonged exposure to light. The sodium azide in the formulation permits direct dilution into standard Tris- or PBS-based blocking and wash buffers commonly used in immunoblotting workflows.