Anti-ZNF50 Antibody

This polyclonal reagent targets ZNF50, a KRAB-domain zinc finger transcription factor encoded on chromosome 19p13.1, and is supplied by Antibodies.com as an unconjugated rabbit IgG preparation at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide, pH 7.2.

The antibody is recommended for Western blot and immunohistochemistry workflows, with documented reactivity against human, mouse, and rat samples, making it useful for comparative studies across these model organisms. Each vial contains 100 µl of ready-to-use antibody, appropriate for multiple blotting membranes or tissue sections, and the formulation includes sodium azide as a preservative to maintain stability during routine benchtop handling.

KRAB-zinc finger proteins such as ZNF50 typically function as sequence-specific transcriptional repressors that recruit KAP1/TRIM28 corepressor complexes and direct heterochromatin formation at target genomic loci, so researchers investigating gene silencing, chromatin remodeling, or the regulatory networks controlled by KRAB-ZNF family members will find this reagent applicable to their work. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents, supporting both chromogenic DAB detection in immunohistochemistry and enhanced chemiluminescence imaging in Western blot applications.