Anti-ZFYVE19 Antibody

The ZFYVE19 target encodes a zinc finger FYVE-type protein that localizes to early endosomes through its phosphatidylinositol 3-phosphate (PI3P)-binding FYVE domain and participates in endosomal sorting of receptor tyrosine kinases such as EGFR, directing cargo toward lysosomal degradation. A rabbit polyclonal antibody from Antibodies.com provides researchers with an unconjugated reagent in a 100 µl vial volume, raised in rabbit and validated for Western blot (WB) and immunohistochemistry (IHC) on human samples. The antibody detects endogenous ZFYVE19 in cell lysates and formalin-fixed tissue sections, supporting studies of endosome-to-lysosome trafficking, FYVE-domain mediated lipid recognition, and receptor downregulation pathways in signal transduction research. Supplied as a liquid aliquot suitable for repeated blotting or staining experiments, this primary antibody is intended for research use in molecular cell biology laboratories investigating membrane trafficking, endocytic regulation, and related cancer cell signaling pathways.