Anti-ZDHHC17 Antibody

This rabbit polyclonal IgG antibody targets ZDHHC17, a Golgi-localized S-palmitoyltransferase (also known as HIP14) that catalyzes post-translational lipid modification of substrate proteins bearing ankyrin-repeat recognition motifs. Supplied by Antibodies.com as a 200 µL unconjugated liquid, the reagent is validated for Western blot detection of the human target and is well suited to studies of DHHC-domain enzymology, neuronal substrate palmitoylation, and Golgi-membrane trafficking. ZDHHC17 palmitoylates neuronal substrates including huntingtin and several SNARE-family proteins, and altered expression of this acyltransferase has been linked to Huntington's disease pathology, making the antibody valuable for researchers working on neurodegeneration, membrane protein acylation, and huntingtin-interacting protein biology. The polyclonal format, raised in rabbit, offers broader epitope coverage for detecting endogenous ZDHHC17 in cell and tissue lysates.