Anti-ZAP70 Antibody

This rabbit polyclonal IgG antibody targets ZAP70, a Syk-family tyrosine kinase that couples T-cell receptor engagement to downstream signaling cascades governing lymphocyte activation, proliferation, and immune synapse formation. Produced by Antibodies.com as a 200 µL unconjugated reagent, it is validated for western blot, immunohistochemistry, and flow cytometry applications on human samples, supporting studies in T-cell biology, thymic development, primary immunodeficiency research (notably ZAP70-deficient SCID), and the characterization of leukemic T-cell populations. The polyclonal format provides recognition of multiple ZAP70 epitopes, which can be useful when probing activation-state-dependent phosphorylation or when working with primary cells where single-clone reagents show variable signal. Compatible with standard immunoblotting and immunostaining workflows.