Anti-ZAP70 Antibody

This polyclonal reagent targets ZAP70, a 70 kDa Syk-family tyrosine kinase that associates with the zeta chain of the T-cell receptor complex and is essential for proximal TCR signal transduction in developing and mature T lymphocytes. Produced in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated antibody ships as a 100 µl vial ready for use in western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation workflows. Cross-reactivity has been verified on human, mouse, and rat samples, supporting comparative studies of T-cell activation, thymic selection, and the signaling deficits linked to ZAP70-deficient severe combined immunodeficiency. Store refrigerated at 4°C and protect from light; the glycerol and azide stabilizers preserve activity across repeated freeze-thaw cycles for short-term bench use. Investigators probing autoimmunity, lymphoma biology, and adoptive immunotherapy rely on the Antibodies.com catalogue for primary antibodies that connect phospho-signaling readouts with tissue-level localization.