Anti-YWHAQ Antibody

Targeting the 14-3-3 theta adapter protein, this Antibodies.com rabbit polyclonal primary antibody enables detection of YWHAQ across human, mouse, and rat samples in western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows. YWHAQ is a phosphoserine/threonine-binding scaffold that participates in neuronal signaling, apoptosis regulation, and cell cycle checkpoint control, so the reagent supports research in neuroscience, cancer biology, and metabolic disease. Supplied as 100 µl of unconjugated antiserum, the polyclonal format offers recognition of multiple epitopes across the target sequence, an advantage when probing conformational variants or post-translationally modified forms. Researchers commonly apply it to investigate YWHAQ expression patterns in brain tissue, to probe interactions with phosphorylated binding partners such as ASK1, FOXO, and Cdc25, and to study how dysregulation of 14-3-3 scaffolding contributes to tauopathy, tumor proliferation, and insulin signaling. Combined use with appropriate secondary antibodies and controlled antigen retrieval conditions supports reproducible detection in both paraffin-embedded tissue sections and cultured cell monolayers.