Anti-YTHDF2 Antibody

This rabbit polyclonal antibody recognizes YTHDF2, an m6A reader protein that binds N6-methyladenosine-modified mRNAs and directs them toward decay. Produced by Antibodies.com, the unconjugated IgG reagent is reactive with human samples and validated for Western blot detection of endogenous YTHDF2 in cell lysates and tissue extracts. Each vial contains 200 µl of affinity-purified antiserum that can be deployed in chemiluminescent or colorimetric WB workflows. Investigators working in RNA epigenetics, post-transcriptional gene regulation, and the molecular biology of acute myeloid leukemia, hepatocellular carcinoma, and embryonic stem cell renewal routinely probe YTHDF2 to characterize m6A-dependent mRNA turnover and stress-response pathways. The polyclonal format increases the probability of recognizing multiple epitopes across the reader domain, which is useful when probing conserved regulatory regions. For best results, store the antibody at -20 °C in working aliquots to limit freeze-thaw cycles and preserve binding activity across multiple experiments.