Anti-YTHDF2 Antibody

YTHDF2 (YTH N6-methyladenosine RNA binding protein 2) is an m6A reader protein that targets modified transcripts for deadenylation and decay, and this rabbit polyclonal IgG reagent from Antibodies.com enables detection of the ~65 kDa target in human samples by Western blot.

The unconjugated primary antibody is supplied as a 100 µl vial, supports flexible pairing with anti-rabbit HRP or fluorescent secondary reagents, and is validated for WB on cell and tissue lysates. YTHDF2 plays a central role in post-transcriptional gene regulation, stress granule assembly, stem cell self-renewal, hematopoietic development, and viral replication, making this reagent useful for studies of RNA methylation biology, cancer signaling, and immune cell function.

Affinity purification reduces off-target binding, and the polyclonal format offers broader epitope coverage for capturing full-length and partially degraded YTHDF2 under denaturing SDS-PAGE conditions. Aliquot upon receipt and store at -20°C, avoiding repeated freeze-thaw cycles to preserve antibody activity across multiple experiments. For research use only.