Anti-YARS2 Antibody

Raised in rabbit against the mitochondrial tyrosyl-tRNA synthetase 2 (YARS2) protein, this polyclonal IgG reagent from Antibodies.com is supplied as 50 µl of unconjugated antisera validated for western blot detection in human, mouse, and rat samples. YARS2 catalyzes the charging of tyrosine onto mitochondrial tRNA-Tyr and supports intramitochondrial translation; loss-of-function variants in the gene are linked to MLHAS (mitochondrial myopathy, lactic acidosis, and hearing loss), a rare oxidative phosphorylation disorder. The antibody is suited to research on mitochondrial aminoacyl-tRNA synthetases, mitochondrial translation, and the molecular pathology of YARS2-associated disease. Store refrigerated and avoid repeated freeze-thaw cycles to preserve activity. For research use only.