Anti-YAP1 Antibody [Assigned #A11326]

This rabbit monoclonal antibody from Antibodies.com targets YAP1, a 65 kDa transcriptional coactivator that acts as a downstream effector of the Hippo signaling pathway. The unconjugated IgG reagent is supplied as a 50 µL vial and is validated for Western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation workflows on human samples.

YAP1 shuttles between the cytoplasm and the nucleus, where it partners with TEAD transcription factors to drive genes involved in cell proliferation, mechanotransduction, and organ size control. Aberrant YAP1 activity is a frequent focus in oncology research and studies of tissue overgrowth, given its links to cancer progression and regenerative biology.

For storage, aliquot the antibody and store at -20°C to preserve binding activity across multiple freeze-thaw cycles. The monoclonal format delivers batch-to-batch consistency across immunoblotting, staining, and cell culture applications.