Anti-XRN2 Antibody

XRN2 (5'-3' exoribonuclease 2) is a nuclear exoribonuclease involved in transcription termination by RNA Polymerase II, rRNA processing, and the turnover of excised intron lariat RNAs. This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and recognizes the XRN2 target across Human, Mouse, and Monkey samples, supporting immunohistochemistry, Western blot, and ELISA workflows in research settings studying RNA metabolism and gene expression.

Provided as a 100 µl volume, the antibody offers flexibility for both exploratory and multi-experiment studies without immediate need for aliquoting. Its unconjugated format allows researchers to conjugate the reagent to fluorophores, enzymes, or biotin depending on their detection platform, making it useful for immunofluorescence, chromatin immunoprecipitation, or co-immunoprecipitation downstream of the validated applications.

Investigating RNA quality control, telomere maintenance, or the integration of transcription and mRNA turnover, scientists can use this reagent to track endogenous XRN2 levels in tissue sections and cell lysates. Standard storage at refrigerated temperatures with aliquoting is recommended to preserve activity across freeze-thaw cycles.