Anti-XRCC6 Antibody

This rabbit polyclonal reagent from Antibodies.com targets XRCC6, the Ku70 subunit of the heterodimeric Ku70/Ku80 complex that initiates non-homologous end joining (NHEJ) for repair of DNA double-strand breaks. Supplied as 100 µl of unconjugated antiserum, it is validated for Western blot and immunohistochemistry on human samples, supporting studies of genomic stability, telomere maintenance, and V(D)J recombination in research use only workflows. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which can be advantageous when probing truncated or post-translationally modified forms of Ku70 in cell lysates and tissue sections. For handling, aliquot upon arrival to limit freeze-thaw cycles and store refrigerated to preserve activity across the product's shelf life; protect from light when not in use. End users often pair this primary antibody with an HRP- or fluorophore-conjugated secondary to enable chemiluminescent detection on Western blots or chromogenic visualization in immunohistochemistry experiments.