Anti-XRCC5 Antibody

This rabbit polyclonal antibody from Antibodies.com targets the XRCC5 protein, the 80 kDa subunit of the Ku heterodimer (Ku80) that binds DNA double-strand breaks and recruits the DNA-dependent protein kinase catalytic subunit to initiate non-homologous end joining. The unconjugated polyclonal reagent is supplied as 100 µl aliquots and is validated for Western blot and immunohistochemistry on human samples, supporting studies in DNA damage response, V(D)J recombination, and telomere maintenance research. The antibody recognizes the native XRCC5 target in cell lysates and fixed tissue sections, producing a band at the expected 80 kDa molecular weight in Western blot applications. Store at -20°C and protect from light to preserve reagent integrity; for short-term use, refrigerated storage at 4°C is acceptable. Intended for research use only, this reagent supports laboratories investigating genome stability, radiation response pathways, and the molecular mechanisms of double-strand break repair in human cells.