Anti-XRCC5 (8H1) Antibody

XRCC5 encodes the 80 kDa Ku80 subunit of the Ku heterodimer, a core component of the non-homologous end joining pathway required for DNA double-strand break repair and V(D)J recombination. The Anti-XRCC5 (8H1) monoclonal antibody from Antibodies.com provides a mouse-derived, unconjugated reagent that detects endogenous Ku80 in human and monkey samples, supporting studies of genomic stability, telomere maintenance, and immune receptor diversification.

Validated for Western blot, immunofluorescence, and immunoprecipitation, this clone is supplied as 50 µl of purified IgG in 0.1 M Tris-Glycine buffer at pH 7.4, with 150 mM sodium chloride, 50% glycerol, and 0.2% sodium azide included as a preservative. Researchers can apply it directly to whole-cell lysates, chromatin fractions, or fixed cell preparations, then pair the unconjugated primary with HRP, fluorescent, or bead-based secondaries chosen for the specific downstream assay.