Anti-XRCC2 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets XRCC2, a DNA repair protein essential for homologous recombination and the faithful repair of DNA double-strand breaks. Raised in rabbit and supplied as an unconjugated reagent in a 100 µl volume, the antibody is validated for Western blot and immunohistochemistry workflows on human samples, supporting studies in genome stability, Fanconi anemia-like pathways, and hereditary breast and ovarian cancer research.

XRCC2 functions within the BCDX2 and CX3 paralog complexes alongside RAD51B, RAD51C, RAD51D, and XRCC3, facilitating RAD51 filament assembly and replication fork protection. Researchers use this reagent to investigate replication stress response, chemoresistance mechanisms, and the contribution of homologous recombination deficiency to tumorigenesis. The polyclonal format provides recognition of multiple epitopes on human XRCC2, while the unconjugated presentation allows flexible pairing with custom reporter labels or secondary detection chemistries for both chromogenic and fluorescence-based IHC.