Anti-XRCC2 Antibody

This polyclonal antibody from Antibodies.com targets XRCC2 (X-Ray Repair Cross Complementing 2), a RAD51 paralog that participates in homologous recombination repair of DNA double-strand breaks. The rabbit reagent is supplied as 100 µl of unconjugated serum, ready for western blot, immunohistochemistry, and immunofluorescence workflows in human, mouse, and rat samples. XRCC2 assembles into the BCDX2 complex alongside RAD51B, RAD51C, and RAD51D, facilitating strand invasion during error-free DNA repair. Loss-of-function variants are linked to genomic instability and have been implicated in hereditary cancer predisposition, including Fanconi anemia-like phenotypes. Investigators studying DNA damage response, replication fork stability, and chemoresistance mechanisms use this reagent to probe XRCC2 expression in cultured cell lines, formalin-fixed tissue sections, and tumor microarrays. The unconjugated format allows flexible pairing with secondary detection reagents of the researcher's choice across immunoblotting and microscopy workflows. For research use only.