Anti-XRCC1 Antibody

Raised in rabbit against the XRCC1 DNA repair scaffold, this polyclonal Primary Antibody from Antibodies.com targets a 70 kDa nuclear phosphoprotein that orchestrates single-strand break repair and base excision repair pathways. The unconjugated reagent is supplied as 100 µl and is validated for western blot, immunohistochemistry, and ELISA workflows in human, mouse, and rat samples, supporting studies of genotoxic stress, PARP-dependent signaling, and genome stability.

Researchers examining DNA damage response, oxidative lesion processing, or recruitment of DNA ligase III and polymerase β to repair foci can apply the antibody to immunoblotting of whole-cell lysates, formalin-fixed tissue sections, and plate-based immunoassays. Storage at -20 °C in working aliquots preserves reactivity across multiple freeze-thaw cycles for repeated use in longitudinal experiments.