Anti-XPO5 Antibody

Polyclonal antibodies raised in rabbit provide specific detection of Exportin 5 (XPO5), a nuclear transport receptor of the importin-β family that mediates export of pre-miRNAs and certain tRNAs from the nucleus to the cytoplasm. This unconjugated reagent from Antibodies.com is validated for Western blot and immunofluorescence workflows and recognizes endogenous XPO5 in human, mouse, and rat samples. Each vial contains 100 µl of affinity-purified antiserum suitable for probing whole-cell or fractionated lysates and for visualizing subcellular localization patterns relevant to miRNA biogenesis studies. The antibody should be stored refrigerated in small aliquots to limit freeze-thaw exposure and preserve binding activity across many experiments. Researchers investigating nucleocytoplasmic shuttling, RNA interference pathways, or the impact of XPO5 missense variants on pre-miRNA export can apply this reagent to confirm expression changes, map distribution between nuclear and cytoplasmic compartments, and validate findings from genetic or knockdown screens.