Anti-XPA Antibody

The XPA antibody from Antibodies.com is a rabbit polyclonal reagent raised against Xeroderma Pigmentosum complementation group A, a zinc-finger DNA damage recognition factor essential for nucleotide excision repair (NER). This unconjugated primary antibody recognizes a conserved epitope on the human, mouse, and rat proteins, supporting studies of UV-induced DNA damage response, global genome repair, and the molecular basis of xeroderma pigmentosum and related photosensitivity disorders. Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl aliquot, it is validated for Western blot and immunohistochemistry workflows. Researchers investigating NER pathway components, UV-signaling networks, or XPA-deficient patient cell models can use this reagent to probe expression patterns, monitor complex assembly with repair partners such as RPA, TFIIH, and ERCC1, and to characterize repair-deficient phenotypes in vitro.