Anti-X-ray repair cross-complementing protein 6 Antibody

This Rabbit polyclonal antibody recognizes X-ray repair cross-complementing protein 6 (XRCC6, also known as Ku70), a ~70 kDa subunit of the Ku heterodimer that binds DNA double-strand breaks and recruits the DNA-dependent protein kinase catalytic subunit during non-homologous end joining repair. Distributed by Antibodies.com as a 100 µg aliquot in an unconjugated format, the reagent is raised in Rabbit and validated for Western blot (WB) and immunohistochemistry (IHC) workflows. Reactivity has been confirmed against human samples, supporting applications in genomic stability research, V(D)J recombination studies, telomere maintenance investigations, and characterization of the cellular response to ionizing radiation. The polyclonal format presents multiple epitope recognition sites on the XRCC6 target, which can improve signal tolerance for partially degraded antigens in fixed tissue sections and lysate preparations.