Anti-WWP2 Antibody

This polyclonal antibody from Antibodies.com targets WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2), a HECT-domain E3 ubiquitin ligase belonging to the Nedd4 family. Supplied as an unconjugated IgG raised in rabbit, it is validated for Western blot detection of endogenous WWP2 in human and rat lysates. Researchers use anti-WWP2 reagents to study ubiquitination-dependent regulation of substrates including Smad transcription factors and PTEN, with relevance to TGF-β signaling, epithelial-mesenchymal transition, and tumor cell proliferation studies. The reagent ships as a 200 µl liquid aliquot in a single vial and is intended for research use only. For long-term stability, store frozen at -20°C and protect from light; aliquot on receipt to limit freeze-thaw cycles. Affinity purification reduces non-specific binding, and the polyclonal format broadens recognition across multiple WWP2 epitopes.