Anti-WRB Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets the WRB protein (tryptophan rich basic protein), an endoplasmic reticulum membrane-resident factor that cooperates with the CAMLG/Get2 partner to mediate insertion of tail-anchored proteins into the lipid bilayer. The unconjugated reagent is supplied as 100 µl of liquid and is validated for Western blot (WB) and immunohistochemistry (IHC) on formalin-fixed tissue sections. The antibody recognizes the human antigen and shows cross-reactivity with mouse and rat orthologues, enabling comparative studies across standard laboratory model organisms. WRB is broadly expressed in secretory cell types and has been linked to congenital heart defects and to disorders arising from mistargeting of tail-anchored cargo, so this primary antibody supports research on membrane biology, cardiac development, and protein biogenesis pathways.