Anti-WRAP53 Antibody

From Antibodies.com, this unconjugated rabbit polyclonal reagent targets human WRAP53 (also referred to as WDR79), a WD40-domain protein whose functional roles include participation in the survival motor neuron complex, maintenance of Cajal body integrity, and trafficking of the telomerase RNA component to telomeres, while the overlapping antisense transcript WRAP53α stabilizes p53 mRNA. The 100 µl vial is intended for research use only and is validated in western blot and immunohistochemistry workflows, supporting studies of telomere biology, the DNA damage response, p53 signaling, and tumor biology in which altered WRAP53 expression has been described across multiple cancer types.

The polyclonal format broadens epitope coverage, which is useful when detecting more than one WRAP53 isoform or when working with samples where target abundance is low. Short-term refrigerated storage is acceptable; for longer-term stability, aliquot and store at -20°C, avoiding repeated freeze-thaw cycles. Each 100 µl vial provides enough material for several western blot or immunohistochemistry runs on cultured human cells or fixed tissue sections.