Anti-WNT3 Antibody

The rabbit polyclonal reagent from Antibodies.com binds human WNT3, a secreted lipid-modified signaling glycoprotein that activates canonical beta-catenin-dependent signaling during embryogenesis and tissue homeostasis.

WNT3 contributes to primitive streak formation, anterior-posterior axis specification, and neural tube patterning, and altered WNT3 expression has been reported in gastric carcinoma, breast cancer, and other malignancies.

The unconjugated IgG is provided at 100 ul volume and is validated for Western blot detection of endogenous human WNT3 protein in cell and tissue lysates. Polyclonal reactivity across multiple epitopes supports recognition of denatured target on membranes and helps when working with limited or partially degraded samples.

Aliquot upon receipt and store refrigerated to preserve antibody activity across repeated experiments. Researchers use this reagent to probe Wnt pathway activation, validate CRISPR knockout or RNAi knockdown of WNT3, and compare expression across developmental stages or tumor samples.