Anti-WNT1 Antibody

A rabbit polyclonal reagent from Antibodies.com raised against WNT1, an evolutionarily conserved secreted signaling glycoprotein that drives canonical β-catenin signaling and embryonic patterning. Supplied as 100 µl of unconjugated antibody solution, this preparation is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human and mouse samples.

WNT1 was first characterized as the int-1 proto-oncogene activated by proviral integration in murine mammary tumors, and subsequent work established it as a founding member of the Wnt family of lipid-modified morphogens. Functional studies have linked WNT1 activity to midbrain and cerebellum development, hematopoietic stem cell maintenance, and dysregulated signaling in several cancer contexts, making it a target of interest for developmental biology and oncology research.

Generated in rabbit and purified as a polyclonal reagent, the antibody recognizes the WNT1 protein in human and mouse preparations. Because it is provided unconjugated, users can conjugate it to fluorophores, enzymes, or biotin in their own labeling protocols. For best results, aliquot on first use and store refrigerated, avoiding repeated freeze-thaw cycles.