Anti-WNK3 Antibody

Antibodies.com offers this rabbit polyclonal primary antibody raised against WNK3, a serine/threonine kinase of the WNK family known for modulating SLC12A cation-chloride cotransporters and implicated in neuronal excitability as well as certain tumor-signaling pathways. The reagent is supplied as 50 µL of unconjugated IgG, validated for use in western blot and immunohistochemistry on Human, Mouse, and Rat specimens. Because the antibody is polyclonal, the immune response recognizes multiple epitopes across the endogenous kinase, which is useful when probing full-length protein in lysates or assessing localized staining in tissue sections. Typical research applications include ion-transport studies in kidney epithelial models, investigations of GABAergic signaling in brain tissue, and expression profiling in glioma and other tumor-derived cell lines. For long-term stability, the contents should be aliquoted after the first thaw and stored frozen at -20 °C, with the vial protected from light and shielded from repeated freeze-thaw cycles. Each preparation is intended for research use only and is paired with appropriate secondary detection reagents to deliver reproducible band and chromogen staining outcomes.