Anti-WNK2 Antibody

Rabbit polyclonal antibody from Antibodies.com targeting WNK Lysine Deficient Protein Kinase 2 (WNK2), a serine/threonine kinase of the WNK family that regulates ion transport and cell volume through modulation of the SPAK/OSR1-NKCC1/KCC signaling cascade. The reagent is supplied as 100 µl of unconjugated stock and is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples.

WNK2 has been characterized as a tumor suppressor in several cancer types, with documented loss-of-function in gliomas and meningiomas, and is studied in the broader context of epithelial ion homeostasis, neuronal signaling, and kinase pathway research. Researchers use this antibody to probe WNK2 protein levels in cell and tissue lysates by WB and to localize WNK2 expression patterns in formalin-fixed paraffin-embedded sections by IHC.

Product attributes

• Host species: Rabbit
• Clonality: Polyclonal
• Reactivity: Human
• Conjugate: Unconjugated
• Validated applications: WB, IHC
• Format: 100 µl vial

For routine use, store at -20°C and avoid repeated freeze-thaw cycles by aliquoting upon receipt. The unconjugated format permits flexible pairing with secondary antibodies and fluorophore or enzyme conjugates of the researcher's choice.