Anti-WNK2 Antibody

This unconjugated rabbit polyclonal IgG from Antibodies.com targets WNK2 (With No Lysine kinase 2), a serine/threonine kinase that regulates intracellular chloride homeostasis through the SPAK/OSR1 signaling cascade. The reagent is supplied in a 200 µL vial and is validated for Western blot detection of the human protein. Investigators apply this antibody to study WNK2 expression in neuronal and glial models, including glioma research where WNK2 acts as a tumor suppressor by inhibiting MEK/ERK signaling. Aliquot the antibody upon receipt, keep refrigerated for short-term use, and store frozen for long-term retention; avoid excessive freeze-thaw cycles. The polyclonal format recognizes multiple epitopes on the target, supporting consistent detection across varied lysate and tissue preparations.