Anti-WNK1 Antibody

Raised in rabbit against the WNK1 (WNK Lysine Deficient Protein Kinase 1) kinase, this polyclonal antibody from Antibodies.com is supplied as an unconjugated 100 µl vial for western blot and immunohistochemistry workflows. WNK1 is a serine-threonine kinase that regulates renal sodium and chloride handling through its downstream SPAK/OSR1 pathway and effects on NCC and NKCC cotransporters, and mutations in the WNK1 gene have been linked to familial Gordon syndrome, also called pseudohypoaldosteronism type II. The reagent recognizes endogenous human and mouse WNK1, supporting studies of kinase expression in kidney tissue sections and in cell or tissue lysates. Storage at -20°C in single-use aliquots helps preserve activity across multiple experiments, and the unconjugated format lets researchers pair the antibody with their own HRP- or fluorophore-labeled secondary reagents for chromogenic or fluorescence detection.