Anti-WIF1 Antibody

Primary antibodies targeting Wnt pathway components must deliver clean signal across multiple species and assay formats. This rabbit polyclonal reagent from Antibodies.com recognizes Wnt Inhibitory Factor 1 (WIF1), a secreted modulator that binds Wnt ligands and dampens canonical Wnt/β-catenin signaling.

Validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), the antibody reacts with human, mouse, and rat samples, supporting work in cancer biology, retinal development, and promoter-hypermethylation studies where WIF1 is frequently silenced. Each vial contains 100 µl of unconjugated antiserum; aliquot upon arrival and refrigerate to preserve activity, avoiding repeated freeze-thaw cycles of the working stock.

The polyclonal format increases the chance of recognizing multiple epitopes on WIF1, which is useful when probing truncated isoforms or partially degraded lysates, and lets laboratories apply the same reagent to cell-line panels, fixed tissue sections, and cultured cells for protein-level confirmation of Wnt-pathway dysregulation.