Anti-WASL Antibody

Produced by Antibodies.com, this rabbit polyclonal reagent targets Wiskott-Aldrich Syndrome-Like protein (N-WASP), an actin cytoskeleton regulator that activates the Arp2/3 complex to drive branched filament assembly. Supplied as 100 µl of unconjugated antiserum, this primary antibody is validated for Western blot and immunohistochemistry on human samples, making it well suited to studies of cell migration, immune synapse formation, vesicle trafficking, and cytoskeletal remodeling in fixed or lysed tissue preparations.

Affinity-purified from rabbit host serum, the reagent reacts with the human WASL target with no significant cross-reactivity against related Wiskott-Aldrich family members under standard assay conditions. Researchers commonly deploy it to probe N-WASP expression across cell lines and primary cultures, including investigation of its role in hematopoietic cell signaling, neuronal development, and pathogen entry mechanisms such as those used by intracellular bacteria. For best results, store the vial refrigerated, protect from light, and prepare small aliquots to limit freeze-thaw cycles when the reagent is in frequent use.

This polyclonal format offers broader epitope coverage than monoclonal alternatives, which is useful when probing conserved regions of WASL or when working with samples where post-translational modification may mask individual epitopes. Pairing the unconjugated antibody with a secondary reporter of choice gives laboratories flexibility across chromogenic IHC, fluorescent Western blot imaging, and immunoprecipitation workflows.